The Endocrine Society updated its vitamin D guidelines on June 3, 2024. The new guideline advised against routine 25(OH)D testing in the general adult population. The Society also recommended against routine follow-up testing to guide vitamin D dosing. The primary reason for recommending against routine testing was the failure to establish 25(OH)D thresholds that prevent disease.
Instead of testing, the Endocrine Society recommends daily empiric vitamin D supplementation for the following groups of people:
- Children aged 1-18 years to prevent rickets and to potentially lower the risk for respiratory tract infections
- Pregnant people to lower the risk for maternal and fetal or neonatal complications
- Adults older than 75 years to lower the risk for mortality
- Adults with prediabetes to lower the risk for type 2 diabetes
The guideline recommended vitamin D doses of 600 IU/d for those aged 1-70 years and 800 IU/d for those older than 70 years. The guideline advised against vitamin D doses that are higher than the recommended daily intake for healthier adults who are younger than 75 years of age.
Reference
Demay MB et al. Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism, published online June 3, 2024; 00: 1–41, https://doi.org/10.1210/clinem/dgae290