The Endocrine Society updated its vitamin D guidelines on June 3, 2024. The new guideline advised against routine 25(OH)D testing in the general adult population. The Society also recommended against routine follow-up testing to guide vitamin D dosing. The primary reason for recommending against routine testing was the failure to establish 25(OH)D thresholds that prevent disease.

Instead of testing, the Endocrine Society recommends daily empiric vitamin D supplementation for the following groups of people:

  1. Children aged 1-18 years to prevent rickets and to potentially lower the risk for respiratory tract infections
  2. Pregnant people to lower the risk for maternal and fetal or neonatal complications
  3. Adults older than 75 years to lower the risk for mortality
  4. Adults with prediabetes to lower the risk for type 2 diabetes

The guideline recommended vitamin D doses of 600 IU/d for those aged 1-70 years and 800 IU/d for those older than 70 years. The guideline advised against vitamin D doses that are higher than the recommended daily intake for healthier adults who are younger than 75 years of age.

Reference

Demay MB  et al. Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism, published online June 3, 2024; 00: 1–41, https://doi.org/10.1210/clinem/dgae290


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